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Rentschler Fill Solutions, Ultragenyx in Fill/Finish Pact

Rentschler to provide fill/finish services for the U.S. commercial supply of Mepsevii

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By: Kristin Brooks

Managing Editor, Contract Pharma

Rentschler Fill Solutions GmbH entered a collaboration with Ultragenyx Pharmaceutical, Inc. for the drug product production of the injectable Mepsevii (vestronidase alfa), a recombinant form of the human enzyme beta-glucuronidase, to treat patients with mucopolysaccharidosis (MPS) VII, a rare genetic disorder.   Mepsevii was developed by U.S.-based Ultragenyx in collaboration with Rentschler Biopharma SE in Germany, and was approved by the U.S. FDA in November 2017. Ultragenyx has also applied...

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